Science Myths

Should we all invest in Blue Light Blocking glasses?

With growing use of electronic devices and virtual learning due to the Covid19 pandemic, concerns about eye health are on the rise. There is a growing belief that blue light from electronic devices can cause retinal damage and accelerate the development of age-related macular degeneration (AMD). AMD is a chronic disease caused by the degeneration of the macula, the central region of the retina, leading to central vision loss(Lim et al., 2012). Blue light blocking glasses have been marketed to reduce risk of retinal damage, and eye fatigue by filtering out blue light. Many of us seem to be convinced that blue light from electronic devices can damage our eyes, especially since we all feel the fatigue and irritation after staring at our screens for long periods. But is blue light really the culprit?

Electromagnetic Spectrum
Figure 1. Electromagnetic spectrum
Adapted from Biorender.com.

What is Blue Light?

Blue light is a high-energy visible light with a wavelength between 400 and 500nm (Taylor et al., 1992). It is perceived by the human eye as blue in color, however, it can also be present in white light which is composed of all the wavelengths of the visible spectrum (Figure 1). Light-emitting (LE) electronic devices are found to emit more blue light than any other color light (Gringras et al., 2015), which is why many worry about the consequences of staring at their screens for long hours.

How do we see color?

The eye is the smallest yet most complex organ in the human body, composed of various parts that work together to aid in vision. Light hits the first layer of the eye, the cornea, which is a transparent thick layer that protects the eye from germs, dust and harmful matter (Zhu et al., 2012). It also filters the damaging ultraviolet light from the sun’s rays and along with the lens aids in focusing the light on the retina (Zhu et al., 2012). Depending on the intensity of the light, the iris will contract or relax, adjusting the size of the pupil to regulate the amount of light that enters the eye. The optimal level of light eventually hits the lens, made from crystallin protein, which further filters the light from the cornea (Zhu et al., 2012). The degree the light is refracted into the eye is adjusted by the contraction and relaxation of ciliary muscles surrounding the lens. The light is finally projected onto the retina where the light signals are processed and transformed into neural signals that can be processed by the brain to perceive an image. The retina contains photoreceptors that allow you to see color (Figure 2). There are four types of photoreceptors, rod cells allow you to see in the dark, and 3 cone cells: red, blue, and green which allow you to see in the daytime and are responsible for registering colors based on the wavelength of the light (Zhu et al., 2012). The fovea is condensed with cone cells and is the most sensitive part of the retina that provides our central vision (Zhu et al., 2012). Surrounding the fovea is the macula, which contains photopigments that further protect the macula and fovea by filtering out short wavelengths of light (Zhu et al., 2012).

Eye Diagram
Figure 2. Structure of the eye
Created with Biorender.com.

When it comes to keeping your eyes healthy and protecting your vision, blue light from electronic devices is the least of your concerns. In fact, we are exposed to far more blue light from the sky than from our computer screens. If being outside on a sunny day does not damage your retina then neither would electronic devices, which are dim by comparison (O’Hagan et al., 2016). Although laboratory studies have shown that blue light can damage retinal cells, these are experiments done on retinal cell cultures in petri dishes or mice that have been exposed to high intensity blue light for long hours (Suter et al., 2000; Youn et al., 2009). In fact, human eyes are different from mice; humans have protective features such as the macular pigments and the blocking ability of the crystalline lens, which absorbs blue light before it reaches the retina (Figure 2). To date, there is no conclusive evidence that suggests that blue light from electronic devices can cause AMD in humans. Compared to aging, smoking, cardiovascular disease, high blood pressure, and being overweight, blue light is a minimal risk factor for the development of AMD. (Armstrong & Mousavi, 2015).  Hence, blue light blocking glasses have no added benefit in protecting against AMD. However, we can protect ourselves from AMD by eating a proper diet, especially foods high in omega-3 fatty acids. Moreover, the eye fatigue and irritation associated with prolonged screen time is unrelated to blue light, but because we do not blink enough when we stare at our screens, our eyes tend to dry out. Dry eyes lead to temporary blurry vision, eye fatigue and irritation (Loh & Redd, 2008). In addition, when you are too focused on the screen, the inner muscles of the eye tighten, resulting in eye strain (Blehm et al., 2005). To battle eye strain, the American Optometric Association recommends following the 20-20-20 rule; every 20 minutes take a 20 second break and look 20 feet away into the distance to allow the muscles to relax and refocus. Also, blinking often and using lubricating eye drops can help prevent your eyes from drying out. 

Although blue light from electronic devices is not harming your retina, it’s not exactly harmless. There is extensive evidence that shows that blue light can affect our biological clock, also known as the circadian rhythm. The circadian rhythm is a natural process that regulates the sleep-wake cycle by responding to light changes in the environment. Specifically, photosensitive retinal ganglion cells, or ipRGCs, play an important role in modulating this cycle(Srinivasan et al., 2009). They do so by sending light input signals to the suprachiasmatic nucleus (SCN) of the hypothalamus, a major circadian oscillator that regulates the production of melatonin – the darkness hormone (Srinivasan et al., 2009). Melatonin is released by the pineal gland in the brain in response to darkness to promote sleepiness and reset the circadian rhythm (Srinivasan et al., 2009). Studies have shown that blue light suppresses melatonin, making you less sleepy (Esaki et al., 2016; Srinivasan et al., 2009). In fact, all different types of light can suppress the melatonin hormone, which is why keeping your room dim before going to bed is highly recommended. However, an experimental study showed that melatonin was suppressed twice as long when people were exposed to blue light (460nm) compared to green light (555nm) (Wahl et al., 2019). Hence, blue light wavelengths have a more potent effect on human circadian rhythm than other short-wavelength visible light (Wahl et al., 2019).   

While exposure to blue light is important for keeping us alert and enhancing our cognitive performance during the day, chronic exposure to blue light around bedtime can compromise sleep quality. Recently, blue light blocking glasses have gained traction in selectively filtering out blue-wavelength light to potentially ameliorate shifts in circadian rhythm caused by blue light. A randomized control trial reported that wearing blue light blocking lenses 2 hours before bedtime for a week had significant improvements in sleep, compared to wearing clear lenses, in individuals with insomnia symptoms (Shechter et al., 2018). Thus, wearing blue light blocking glasses can help improve sleep quality, especially for individuals working night shifts or spending time on their computers before going to sleep. Alternatively, putting your devices away 2 or 3 hours before going to bed can help improve sleep quality and duration. 

Blue light blocking glasses may have some benefits in reducing melatonin suppression at night, however, there is no evidence that it can help protect against retinal damage. To maintain eye health it’s important to keep them lubricated and relaxed during long computer sessions. Following the 20-20-20 rule, blinking often, and using lubricating eye drops could significantly reduce eye strain and irritation. Moreover, dimming lights and screens before bedtime can help reduce the impact of blue light on your biological clock and improve sleep quality.     

References

Armstrong, R. A., & Mousavi, M. (2015). Overview of Risk Factors for Age-Related Macular Degeneration (AMD). Journal of Stem Cells, 10(3), 171–191.

Blehm, C., Vishnu, S., Khattak, A., Mitra, S., & Yee, R. W. (2005). Computer Vision Syndrome: A Review. Survey of Ophthalmology, 50(3), 253–262. https://doi.org/10.1016/j.survophthal.2005.02.008

Esaki, Y., Kitajima, T., Ito, Y., Koike, S., Nakao, Y., Tsuchiya, A., Hirose, M., & Iwata, N. (2016). Wearing blue light-blocking glasses in the evening advances circadian rhythms in the patients with delayed sleep phase disorder: An open-label trial. Chronobiology International, 33(8), 1037–1044. https://doi.org/10.1080/07420528.2016.1194289

Gringras, P., Middleton, B., Skene, D. J., & Revell, V. L. (2015). Bigger, Brighter, Bluer-Better? Current Light-Emitting Devices – Adverse Sleep Properties and Preventative Strategies. Frontiers in Public Health, 3. https://doi.org/10.3389/fpubh.2015.00233

Lim, L. S., Mitchell, P., Seddon, J. M., Holz, F. G., & Wong, T. Y. (2012). Age-related macular degeneration. The Lancet, 379(9827), 1728–1738. https://doi.org/10.1016/S0140-6736(12)60282-7

Loh, K., & Redd, S. (2008). Understanding and Preventing Computer Vision Syndrome. Malaysian Family Physician : The Official Journal of the Academy of Family Physicians of Malaysia, 3(3), 128–130.

O’Hagan, J. B., Khazova, M., & Price, L. L. A. (2016). Low-energy light bulbs, computers, tablets and the blue light hazard. Eye, 30(2), 230–233. https://doi.org/10.1038/eye.2015.261

Shechter, A., Kim, E. W., St-Onge, M.-P., & Westwood, A. J. (2018). Blocking nocturnal blue light for insomnia: A randomized controlled trial. Journal of Psychiatric Research, 96, 196–202. https://doi.org/10.1016/j.jpsychires.2017.10.015

Srinivasan, V., Spence, W. D., Pandi-Perumal, S. R., Zakharia, R., Bhatnagar, K. P., & Brzezinski, A. (2009). Melatonin and human reproduction: Shedding light on the darkness hormone. Gynecological Endocrinology, 25(12), 779–785. https://doi.org/10.3109/09513590903159649

Suter, M., Remé, C., Grimm, C., Wenzel, A., Jäättela, M., Esser, P., Kociok, N., Leist, M., & Richter, C. (2000). Age-related Macular Degeneration: THE LIPOFUSCIN COMPONENTN-RETINYL-N-RETINYLIDENE ETHANOLAMINE DETACHES PROAPOPTOTIC PROTEINS FROM MITOCHONDRIA AND INDUCES APOPTOSIS IN MAMMALIAN RETINAL PIGMENT EPITHELIAL CELLS*. Journal of Biological Chemistry, 275(50), 39625–39630. https://doi.org/10.1074/jbc.M007049200

Taylor, H. R., West, S., Muñoz, B., Rosenthal, F. S., Bressler, S. B., & Bressler, N. M. (1992). The Long-term Effects of Visible Light on the Eye. Archives of Ophthalmology, 110(1), 99–104. https://doi.org/10.1001/archopht.1992.01080130101035

Wahl, S., Engelhardt, M., Schaupp, P., Lappe, C., & Ivanov, I. V. (2019). The inner clock—Blue light sets the human rhythm. Journal of Biophotonics, 12(12), e201900102. https://doi.org/10.1002/jbio.201900102

Youn, H.-Y., Chou, B. R., Cullen, A. P., & Sivak, J. G. (2009). Effects of 400nm, 420nm, and 435.8nm radiations on cultured human retinal pigment epithelial cells. Journal of Photochemistry and Photobiology B: Biology, 95(1), 64–70. https://doi.org/10.1016/j.jphotobiol.2009.01.001

Zhu, J., Zhang, E., & Rio-Tsonis, K. (2012). Eye Anatomy. https://doi.org/10.1002/9780470015902.a0000108.pub2